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Series 7: The Last Mile of Brain Science

SERIES 7: THE LAST MILE OF BRAIN SCIENCE AUTHOR: KJ Lavan We Are Democratizing Detection Before Democratizing Care The next crisis in #Alzheimer’s disease may not be a shortage of scientific breakthroughs. It may be a shortage of systems capable of using them. The science is advancing rapidly. Lecanemab and donanemab can slow progression in appropriately selected people with early Alzheimer’s disease. But these therapies require confirmation of amyloid pathology, specialist evaluation, infusions, MRI monitoring and management of amyloid-related imaging abnormalities. ( U.S. Food and Drug Administration ⁠) In July 2026, the FDA approved an at-home starting dose of lecanemab—another step toward making treatment more accessible.  Yet, moving administration closer to the home does not eliminate the need for diagnosis, patient selection, safety surveillance and coordinated clinical oversight. https://www.fda.gov/drugs/news-events-human-drugs/fda-approves-first-home-starting-dose-alzheim...

The Global Cognitive Resilience Economy: The Next Strategic Layer Beyond National Dementia Plans

The Global Cognitive Resilience Economy: The Next Strategic Layer Beyond National  Dementia Plans Briefing Note for Alzheimer’s Disease International Leadership and Board of Directors Prepared by: KJ Lavan Date: June 2026 ⸻ Executive Summary Over the past decade, Alzheimer’s Disease International (ADI) has played a pivotal role in advancing  national dementia plans worldwide, helping move dementia from a neglected condition to a recognized public policy priority. This achievement represents one of the most important global health policy successes of the 21st century. Yet a new reality is emerging. Dementia is no longer solely a health-sector challenge.  It is increasingly becoming a systemic economic, workforce, fiscal, and societal issue with implications extending far beyond healthcare delivery. As populations age and longevity increases, the strategic question facing governments is evolving: How do nations preserve cognitive capacity, productivity, inde...