Possibilities

  📊  From Diagnosis to Infrastructure: The System-Level Transformation of Alzheimer’s Disease Author: KJ Lavan ⸻ Executive Summary Alzheimer’s disease is undergoing a structural transition from a symptom-based neurological condition to a  biologically defined, system-managed disease . Three converging domains— therapeutics, biomarkers, and diagnostics —are reshaping not only clinical care, but also the  economic and policy architecture of ageing societies . This transition introduces a new paradigm: Alzheimer’s is no longer defined solely by cognitive decline, but by  measurable biological signals that determine access to intervention . Recent advances including disease-modifying therapies, blood-based biomarkers, and scalable diagnostic pathways—are accelerating this shift toward  earlier detection and intervention Alzheimer’s Association  (2025). ⸻ 1. Therapeutics: From Validation to Optimization The approval and expansion of anti-amyloid therapies ...