Possibilities

By: KJ Lavan The Convergence of Astrocyte Biology, Metabolism, and Neuropsychiatric Health A lready quietly unfolding at the frontiers of neuroscience and precision medicine is the era of  “metabo-neuro” interventions , and astrocytes are a key to unlocking it. 🔬 Why Astrocytes? Astrocytes are no longer seen as just "support cells" in the brain. They are: Metabolic gatekeepers  – regulating glucose and lactate delivery to neurons. Neurotransmitter modulators  – recycling glutamate, shaping synaptic transmission. Neuroimmune mediators  – producing cytokines, responding to systemic inflammation. Circadian regulators  – influencing sleep, feeding, and energy homeostasis. In essence, astrocytes  translate metabolic cues into neural outcomes. 🔁 The Metabo-Neuro Feedback Loop There’s a  bi-directional dialogue  between metabolic health and brain health: Systemic metabolic dysfunction  (e.g., insulin resistance, obesity) → astrocyte inflammation →...